Combination Cancer Drugs Before Surgery for Stomach Cancer
Part of Cancer, Digestive system clinical trials.
This trial tests whether giving immunotherapy and chemotherapy drugs before surgery can help treat stomach cancer that has a specific protein marker (claudin 18.2). The goal is to shrink the tumor and improve outcomes for patients whose cancer can be surgically removed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with adenocarcinoma (a type of cancer) of the stomach or the junction where the stomach meets the esophagus (food pipe)
- Your tumor shows the claudin 18.2 protein marker (a genetic feature) on at least 25% of cancer cells
- Your cancer is advanced (stage T3-4 with lymph node involvement) but can be surgically removed with curative intent
- Your cancer does NOT have the HER2 protein marker
- You are in good overall health with good organ function and an expected lifespan of at least 12 months
- You have not previously received targeted therapies against claudin 18.2
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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