Testing a blood marker to diagnose excessive thirst and urination
Treatments studied
Part of Hormones & metabolism, Kidney & urinary, Women’s health & pregnancy clinical trials.
This study helps doctors figure out why some people drink and urinate excessively. Researchers will measure a hormone called copeptin in your blood after giving you fluids, to find out if your excessive drinking and urination is caused by a specific hormone problem (AVP deficiency) or something else.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18 or older
- Urinate more than 40 ml per kilogram of body weight per day (or more than about 2.8 liters per day for a 70 kg person) and drink more than 3 liters of fluid per day
- Urine is very dilute (less concentrated than normal), or you already have a diagnosis of AVP deficiency
- Your excessive urination is not caused by diabetes, high blood calcium, or low potassium
- You do not have kidney disease (eGFR must be at least 60), severe heart failure, severe liver disease, or untreated thyroid or adrenal problems
- You are not pregnant, breastfeeding, or in another clinical trial within the last 30 days
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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