Finerenone after heart valve replacement
Treatments studied
Part of Heart & circulation clinical trials.
This study tests if the drug finerenone helps people with heart failure who had a heart valve replacement (TAVI) for severe aortic stenosis. The goal is to see if it improves heart function and outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 65 years or older.
- You have severe narrowing of your aortic valve (the main heart valve) and are getting a TAVI procedure (replacement through a tube in the leg).
- You have symptoms like shortness of breath or fatigue (New York Heart Association class II or more).
- Your heart's pumping ability (ejection fraction) is 40% or higher before the procedure.
- You do not have untreated high potassium levels, severe kidney problems, or a recent heart attack or stroke (within the last month).
- You are not allergic to finerenone or similar drugs.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new medicine called finerenone to see if it can reduce heart scarring and improve heart function in people with a certain type of heart failure (preserved ejection fraction). If you qualify, you may help researchers learn if this treatment can help you feel better and stay out of the hospital.
This trial tests a medication called finerenone to see if it helps people hospitalized for heart failure live longer and have fewer heart-related problems. It may be an option for those with a certain type of heart failure where the heart's pumping strength is mildly reduced or normal.
This study tests whether finerenone, a new type of drug, can help people with heart failure who cannot take standard steroid-based MRAs (a kind of heart medication) because of side effects or other reasons. It aims to see if it improves symptoms and is safe for you.
This study tests whether finerenone, a medication that may help the heart work better, can improve electrical stability in people with a certain type of heart failure (HFpEF). It aims to reduce irregular heart rhythms and improve overall heart health.
This trial tests whether taking finerenone after a heart procedure to fix irregular heartbeat can help prevent atrial fibrillation from coming back. It's for people having their first such procedure and aims to improve long-term heart rhythm health.
This trial tests if starting finerenone early helps patients hospitalized with heart failure who have symptoms like shortness of breath or swelling. It aims to see if the drug is safe and effective when given soon after admission.
Hear when a new TAVI(Transcatheter Aortic Valve Implantation) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.