Finerenone for heart failure with preserved ejection fraction
Part of Heart & circulation clinical trials.
This study tests whether a medication called finerenone can reduce scarring in the heart and improve heart function in people with heart failure who have ejection fractions of 40% or higher. You may be eligible if you've recently had heart failure symptoms requiring emergency care or medication changes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18–80 years old
- Symptomatic heart failure (NYHA class II–IV) with recent hospitalization or worsening symptoms in the past 3 months
- Heart ejection fraction ≥40% (measured by echocardiography or cardiac MRI within 30 days)
- Evidence of heart scarring (fibrosis) on cardiac MRI with ECV ≥27%
- Elevated NT-proBNP blood marker (≥300 pg/mL in regular heart rhythm, ≥900 pg/mL if you have atrial fibrillation)
- Adequate kidney function (eGFR ≥25) and normal potassium levels (<5.0 mmol/L)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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