Oral tablet for bronchiectasis flare-ups
Part of Lungs & breathing clinical trials.
This study tests an oral tablet called florensocatib (also known as CHF10196) to see if it can reduce lung infections in people with bronchiectasis. It is given alongside your usual care, and may help you have fewer flare-ups.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 12 and 85 years old.
- You have a doctor-confirmed diagnosis of bronchiectasis, shown on a chest CT scan (done within the last 5 years, or you agree to have a new one).
- In the past year, you have had at least one lung infection treated with antibiotics (or two infections if you are an adult without other risk factors).
- You are able to produce a sputum (phlegm) sample if you are an adult.
- You do not smoke and are willing to avoid all forms of smoking (cigarettes, e-cigarettes, vaping) during the trial.
- You are not currently having a lung infection (exacerbation) and have not had one in the 4 weeks before screening.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if a new drug, GSK3862995B, is safe and effective for adults with bronchiectasis. It might help reduce lung infections and improve symptoms.
This trial studies whether long-term Staphylococcus albicans tablets can safely reduce bronchiectasis flare-ups and improve symptoms. It may help people with frequent infections/attacks due to bronchiectasis.
This trial tests an inhaled medication for people with bronchiectasis, a lung condition causing chronic cough and mucus. It first checks safety in healthy volunteers, then studies how the drug works in people with bronchiectasis.
This trial tests whether a new medication, BI 1291583, can help people with bronchiectasis reduce lung infections and symptoms. You may join if you have had at least one or two lung flare-ups in the past year.
This study tests whether a common antibiotic called azithromycin can help prevent flare-ups (sudden worsening) of bronchiectasis—a lung condition where airways become permanently enlarged and damaged. Patients will take azithromycin or a placebo for 12 months to see if it reduces how often they get sick.
This trial tests a new medicine, HSK31858, for people with non-cystic fibrosis bronchiectasis (a lung condition causing chronic cough and infections). It aims to see if the drug reduces lung flare-ups and improves symptoms.
Hear when a new Bronchiectasis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.