CAR NK cells for recurrent glioblastoma brain tumors
Treatments studied
Part of Cancer clinical trials.
This trial tests engineered immune cells (called NK cells) that are designed to fight glioblastoma, a deadly brain cancer. The cells are injected directly into the tumor and may help patients whose cancer has come back after standard treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with recurrent glioblastoma (a type of brain cancer that has returned) and had prior radiation and chemotherapy
- Your tumor is no larger than 5 cm (about 2 inches) and is a single tumor, not multiple tumors in different locations
- Your overall health and ability to perform daily activities is fairly good (Karnofsky score above 70, meaning you can carry out most normal activities)
- Your blood counts, liver function, and kidney function are healthy enough based on recent lab tests
- You have not had certain prior brain treatments like brachytherapy (implanted radiation) or other locally injected therapies
- You are willing to use birth control if you can have children and commit to follow-up visits after the treatment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a new treatment using engineered immune cells (CAR-NK cells) that target two markers found on glioblastoma tumors. The treatment is given directly into the brain to fight tumors that have come back after standard therapy.
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