Immune treatment for stubborn infections in aids
Treatments studied
Part of Immune system & allergy, Infections clinical trials.
This study tests whether giving an immune checkpoint inhibitor (a drug that helps your immune system fight infections) can help treat opportunistic infections in people with AIDS that are hard to get rid of. It aims to see if the treatment is safe and works for these stubborn infections.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older and have HIV.
- You must have had an infection that did not get better even with standard treatment. Examples include certain viruses, pneumonia, meningitis, tuberculosis, or other serious infections.
- Your immune system must show specific changes: either high PD-1 levels on some cells or a weak response in a special blood test.
- You cannot have an autoimmune disease or have had an organ or stem cell transplant.
- You cannot have had previous treatment with an immune checkpoint inhibitor (like pembrolizumab or nivolumab).
- You must be willing to use effective birth control during the study and for 6 months after.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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