Study of POTS body chemical signals and blood pressure control
Treatments studied
Part of Brain & nervous system clinical trials.
This trial studies people with POTS (a condition where heart rate rises when you stand) and compares them with people without POTS. It tests body “adrenergic” (stress-chemistry) signals and how the body handles posture, which may help researchers find better ways to manage POTS.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have already been diagnosed with POTS (or you are a control participant without POTS)
- You are age 18 to 60
- You can provide informed consent and are willing to join the study
- You are not a smoker
- You do not have a clear medical cause for your “postural” (standing-related) fast heart rate, such as acute dehydration
- You do not have major heart, lung, liver, or blood problems based on past history or tests
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study measures how breathing patterns and heart rate/blood pressure change when you move from lying to standing in people with POTS. It may help researchers understand symptoms better and improve ways to manage them.
This study compares two heart-rate medicines—propranolol and ivabradine—to see which better improves symptoms in people with POTS. It uses a “crossover” design, meaning you may try one medicine and then switch to the other.
This trial studies whether an autoimmune (immune system–related) process is involved in postural tachycardia syndrome (POTS), a condition where your heart rate rises when you stand. The study may help researchers understand what causes POTS and how it could be treated or monitored.
This trial tests whether pyridostigmine helps people with postural tachycardia syndrome (POTS), which causes heart rate to rise when you stand up and can lead to unpleasant symptoms. You would be screened based on your tilt-table heart-rate response and your standing-related symptoms.
This study looks at how a specific brain–vagus nerve connection works in people with POTS and tries to understand what happens over time. It may help researchers better explain symptoms and other health problems that can occur with POTS.
This study looks at how improving “vagal nerve” function—through breathing-related training—may change brain connectivity in people with POTS, near-fainting, or fainting upon standing. It’s meant to better understand whether these changes could help symptoms and inform future treatments.
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