Clin2
NCT07811687Possibly a fitRecruiting

Liver and spleen surgery for liver cancer with cirrhosis

Liver CirrhosisHCC - Hepatocellular CarcinomaHypersplenism

Part of Blood & lymphatic, Cancer, Digestive system clinical trials.

This study tests whether removing part of the liver along with the spleen during laparoscopic (keyhole) surgery helps improve liver function and the immune system in people with liver cancer and cirrhosis. If you qualify, you may have better surgical outcomes and recovery.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
30 people
Ages
18 years to 80 years
Study type
Observational

Who can take part

  • You are between 18 and 80 years old.
  • You have hepatocellular carcinoma (liver cancer) that is either one tumor 5 cm or smaller, or up to 3 tumors each 3 cm or smaller.
  • You have cirrhosis (liver scarring) with an enlarged spleen and a low platelet count (under 80,000).
  • Your liver function is good enough for surgery (Child-Pugh class A or B).
  • You have not had liver or spleen surgery before, and you do not have other serious health problems or infections.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07585773Not yet recruiting
Spleen removal surgery and kidney function in cirrhosis patients

This study tests whether removing an enlarged spleen through keyhole surgery can improve kidney function in people with cirrhosis and an overactive spleen. The trial follows patients for two years to see if the surgery helps protect the kidneys.

Yangzhou, Jiangsu
NCT07588373Not yet recruiting
Spleen removal surgery for cirrhosis patients with enlarged spleen

This study looks at whether removing an enlarged spleen (splenectomy) in people with cirrhosis can improve their blood fat (lipid) levels over two years. It may help those with low blood counts due to an overactive spleen.

Yangzhou, Jiangsu
NCT07462091Recruiting
Nerve-guided surgery for enlarged spleen and bleeding risk

This study tests a special surgery using a nerve-guided technique to remove the enlarged spleen and reduce bleeding risk in people with cirrhosis and portal hypertension. It may help if you have an enlarged spleen and have had bleeding related to liver disease.

Yangzhou, Jiangsu
NCT07490405Not yet recruiting
Comparing two procedures for cirrhosis bleeding and enlarged spleen

This study compares two procedures to treat bleeding from enlarged veins in the esophagus or stomach for people with cirrhosis and an overactive spleen. The goal is to see which approach reduces bleeding risk and improves blood counts over time.

Yangzhou, Jiangsu
NCT06069947Not yet recruiting
Liver transplant for cirrhosis with early liver cancer

This study tests whether giving a liver transplant to people with cirrhosis and small liver tumors from hepatitis B can help them live longer. It compares outcomes for patients who meet specific tumor size criteria.

NCT07518706Not yet recruiting· Phase 2
Two-drug treatment before surgery for early liver cancer

This study tests whether giving a combination of two drugs—tislelizumab (an immunotherapy that helps your immune system fight cancer) and lenvatinib (a targeted therapy that blocks tumor growth)—before surgery can improve outcomes for people with early-stage liver cancer (a single tumor 2-5 cm) when the surgery is likely to have a narrow margin. You would receive the drugs for a few weeks before your scheduled surgery, and then have the surgery as planned. This approach may help reduce the chance of the cancer coming back.

Hear when a new Liver Cirrhosis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.