Thiotepa-Based Stem Cell Transplant for Chronic Myelomonocytic Leukemia
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests a chemotherapy regimen (thiotepa-containing preparation) combined with a stem cell transplant from a donor to treat chronic myelomonocytic leukemia (CMML), a rare blood cancer. The goal is to see if this approach helps patients with intermediate-to-high risk disease achieve remission.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have confirmed CMML diagnosis that is intermediate-2 or high-risk
- You are at least 18 years old
- You have a suitable stem cell donor (family member, matched unrelated donor, or partial match)
- Your heart, liver, kidneys, and lungs are functioning well enough for transplant
- You don't have active infections, HIV, hepatitis B or C, or recent stroke
- You're not pregnant, breastfeeding, or unwilling to commit to this treatment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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