Blood stem cell transplant with lower-intensity chemo for blood cancers
Treatments studied
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests a stem cell transplant using milder chemotherapy (treosulfan and fludarabine) followed by a drug called cyclophosphamide to prevent graft-versus-host disease. It aims to make transplant safer for people with blood diseases who cannot handle standard high-dose chemotherapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Ages 2 to 75 years old.
- Must have a matched relative, unrelated donor, or half-matched (haploidentical) relative.
- Adequate heart, lung, liver, and kidney function (doctors will check).
- No uncontrolled infections or active HIV.
- No active cancer in the brain or spinal fluid.
- At least 3 months since a previous stem cell transplant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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