Clin2
NCT07589400Possibly a fitNot yet recruiting

Testing ACT500 for fatty liver with chronic hepatitis B

Metabolic Dysfunction-associated Steatotic Liver DiseaseChronic Hepatitis b

Part of Digestive system, Infections clinical trials.

This study tests a new medicine called ACT500 for people who have both fatty liver disease and chronic hepatitis B. The goal is to see if it is safe and how well it works. It might help reduce fat in the liver and improve liver health.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
24 people
Ages
18 years to 60 years
Study type
Interventional

Who can take part

  • You are between 18 and 60 years old.
  • You have had hepatitis B for more than 6 months and are currently taking antiviral medication for it.
  • You have fatty liver, confirmed by a special MRI scan showing at least 10% fat in your liver.
  • Your liver stiffness is between 8 and 12 kPa (measured by FibroScan), or a recent biopsy shows moderate liver scarring (stage F2 or F3).
  • You have at least one metabolic risk factor, such as being overweight, having high blood sugar, high blood pressure, or abnormal cholesterol levels.
  • You are not pregnant or breastfeeding, and you agree to use reliable birth control during the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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