Half-dose plasma exchange and blood cleaning for sudden liver failure
Part of Digestive system clinical trials.
This trial tests a procedure that cleans your blood (called plasma exchange) given at half the usual dose, along with other detox methods, to help people with sudden liver failure. It aims to help your liver recover or support you while you wait for a transplant.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have been told you have acute-on-chronic liver failure, which is a sudden worsening of a long-term liver disease that can be caused by infection, bleeding, alcohol, or other triggers.
- You need to be in the intensive care unit (ICU) for treatment.
- Your liver function tests must show high bilirubin (a waste product) and abnormal blood clotting (INR).
- You must be either waiting for a liver transplant or, if a transplant isn't an option, your doctors plan to give supportive care.
- You cannot be pregnant, have certain severe lung or heart diseases, advanced cancer, or be too frail.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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