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NCT07857434Possibly a fitNot yet recruiting

Low-volume plasma exchange for liver failure

Acute on Chronic Liver Failure (ACLF)

Treatments studied

Part of Digestive system clinical trials.

This trial tests whether giving a smaller amount of a blood-cleaning treatment (plasma exchange) can help people with sudden liver failure on top of long-term liver disease. It aims to improve liver function and overall outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
840 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You are between 18 and 65 years old.
  • You have liver failure that happened suddenly because of chronic liver disease, with high bilirubin and a blood clotting test (INR) above 1.5.
  • Your liver failure is at a stage 1 or 2 (not the most severe stage).
  • You do not have cancer, are not pregnant or breastfeeding, and do not have HIV or other immune problems.
  • You have not had a organ transplant and are not in end-stage organ failure (like needing dialysis or a ventilator).
  • Your platelet count is at least 50 × 10⁹/L, and you do not have severe bleeding or a serious allergy to the treatment.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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