Clin2
NCT07598318Possibly a fitNot yet recruiting

New drug plus standard treatment for advanced bile duct cancer with EGFR

Cholangiocarcinoma

Treatments studied

Part of Cancer clinical trials.

This study tests a new drug called becotatug vedotin, added to standard chemotherapy, for advanced bile duct cancer that has a specific protein called EGFR. The goal is to see if this combination helps shrink tumors or slow the cancer better than standard treatment alone.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
164 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have been diagnosed with bile duct cancer (including cancer of the gallbladder or bile ducts inside or outside the liver) that cannot be removed by surgery or has spread to other parts of the body.
  • You have already tried at least one previous chemotherapy treatment for your cancer, and it did not work or stopped working.
  • A test on your tumor sample shows that it has a protein called EGFR (this is sometimes called a 'positive' result).
  • You are in generally good health and able to take care of yourself (doctors call this 'ECOG 0-1').
  • You are willing to use effective birth control during the study and for 8 weeks after the last dose (if you or your partner could become pregnant).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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