Pregabalin and Movement Therapy for Knee Osteoarthritis Pain
Part of Bones, joints & muscles, Brain & nervous system, Pain clinical trials.
This trial tests whether a nerve pain medication called pregabalin, applied through ultrasound waves to your knee, combined with gentle movement exercises, can reduce pain in advanced knee osteoarthritis. You'll attend 16 treatment sessions over 4 weeks to see if this combination helps.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Diagnosed with Grade III knee osteoarthritis (confirmed by X-ray within the past year or a new X-ray)
- Evidence of nerve-related pain in the knee using a DN-4 questionnaire (score of 4 or higher)
- Age 40–70 years old
- Able to attend 4 sessions per week for 4 consecutive weeks (16 total sessions)
- No recent knee injections (corticosteroid or hyaluronic acid) within 3 months
- No metal implants, pacemakers, or electronic devices in your body that would prevent ultrasound treatment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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