Clin2
NCT07599007Possibly a fitNot yet recruiting

Repotrectinib safety study for ROS1 or NTRK positive cancers

Non-Small Cell Lung Cancer

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This trial is a safety follow-up study for people who are already being treated with repotrectinib in Korea. It looks at how well the drug works and what side effects may occur in patients with ROS1-positive lung cancer or NTRK-positive solid tumors.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
10 people
Ages
12 years and older
Study type
Observational

Who can take part

  • You must be 19 years or older if you have non-small cell lung cancer, or 12 years or older if you have another type of solid tumor.
  • Your tumor must have a specific gene change called ROS1 or NTRK gene fusion, confirmed by a local test.
  • Your cancer must be locally advanced (spread nearby) or metastatic (spread to other parts of the body).
  • You must agree to sign a written consent form to participate.
  • You cannot have received repotrectinib for a use or at a dose not approved in Korea, and you must not have any medical reason that makes repotrectinib unsafe for you.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07008287Recruiting
Taletrectinib for ROS1+ lung cancer with brain spread

This study gathers real-world experience with the targeted drug taletrectinib for people with a specific type of advanced lung cancer (ROS1-positive) that has spread to the brain. Participation may help doctors better understand how well the drug works in everyday practice.

Hangzhou, Zhejiang
NCT06694129Not yet recruiting
Targeted therapy for advanced ROS1-positive lung cancer

This study looks at how well a targeted therapy works for people with advanced non-small cell lung cancer that has a specific genetic change called ROS1. It aims to see if this treatment can help control the cancer and improve outcomes.

NCT06564324Recruiting· Phase 3
Comparing taletrectinib to standard therapy for ROS1-positive lung cancer

This study compares a new targeted therapy pill (taletrectinib) to standard treatments for people with advanced ROS1-positive lung cancer. The goal is to see if taletrectinib works better at shrinking tumors and delaying cancer growth.

Hefei, Anhui
NCT07199959Recruiting
Study on why entrectinib stops working in ROS1 lung cancer

This study looks at why the targeted drug entrectinib stops working in some people with ROS1-positive lung cancer. Participants will give blood or tumor samples before and after treatment to help researchers understand resistance.

Shanghai, Shanghai Municipality
NCT06552234Recruiting· Phase 2
Study of repotrectinib for older or frail patients with ROS1-positive lung cancer

This trial tests an oral targeted therapy called repotrectinib in people with advanced non-small cell lung cancer (NSCLC) that has a change in the ROS1 gene. It is designed for patients who are either 70 or older, or have a lower performance status (ECOG 2 or higher), meaning they may be more frail or have more symptoms. The goal is to see if repotrectinib can help shrink or control the cancer.

Aix-en-Provence, Bouches Du Rhône
NCT03093116Recruiting· Phase 1/Phase 2
Repotrectinib for ALK, ROS1, or NTRK tumor gene changes

This trial studies repotrectinib, a targeted medicine, in people with advanced solid tumors that have specific gene rearrangements (ALK, ROS1, or NTRK). It may help shrink tumors or control cancer growth based on the patient’s tumor genetic result.

Duarte, California

Hear when a new Non Small Cell Lung Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.