New myeloma treatment without stem cell transplant
Treatments studied
Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy clinical trials.
This trial tests a combination of four drugs (isatuximab, iberdomide, bortezomib, and dexamethasone) for newly diagnosed multiple myeloma in patients who cannot or choose not to have a stem cell transplant. The goal is to see if this combination helps control myeloma and improve survival.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Recently diagnosed with multiple myeloma (no prior myeloma treatment, though some steroid or radiation therapy may be allowed)
- Not able to have a stem cell transplant, or willing to delay it until later
- Measurable myeloma in blood or urine tests showing protein or light chains
- Blood counts and liver/kidney function within acceptable ranges
- Able to take blood-thinning medication to prevent clots
- Willing to use contraception and avoid pregnancy during and after treatment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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