ATV-1601 Treatment for Hereditary Hemorrhagic Telangiectasia
Part of Blood & lymphatic, Genetic & congenital, Heart & circulation clinical trials.
This trial tests a new drug called ATV-1601 in people with HHT, a genetic condition that causes abnormal bleeding and blood vessel problems. The drug aims to reduce bleeding and anemia caused by HHT.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed diagnosis of HHT (hereditary hemorrhagic telangiectasia), a genetic bleeding disorder
- Your HHT is moderate to severe with a specific symptom score of 4 or higher
- You have anemia or needed at least one blood transfusion in the past 6 months
- Your blood, kidney, and liver function tests are adequate for the study
- You are not pregnant, not breastfeeding, and able to use effective birth control during and after the study
- You have not taken an AKT inhibitor before (a type of cancer drug)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests a new drug called DIAG723 in adults with hereditary hemorrhagic telangiectasia (HHT), a genetic condition that causes abnormal blood vessels and bleeding. Depending on which part of the study you qualify for, the drug may help reduce nosebleeds, improve anemia, or help with lung blood vessel problems caused by HHT.
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