Kidney Transplant Outcomes in Denys-Drash Syndrome
Part of Cancer, Genetic & congenital, Hormones & metabolism, Kidney & urinary, Women’s health & pregnancy clinical trials.
This study looks at whether children with Denys-Drash syndrome (a rare genetic condition affecting the kidneys) who receive kidney transplants have a higher risk of developing a type of cancer called lymphoproliferative disorder. Researchers will compare outcomes in children with this syndrome to similar children without it.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You were under 18 years old when you received your kidney transplant
- You have a diagnosis of Denys-Drash syndrome (confirmed by a genetic test showing WT1 gene changes)
- Your kidney transplant was performed between 2000 and 2022 at a participating French hospital
- You are currently being followed at one of the study hospitals in France
- You are taking immunosuppressant medications (drugs to prevent transplant rejection)
- You did not have any lymphoproliferative disorder or blood cancer before your transplant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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