Study of immune cell risk after kidney transplant in Denys-Drash syndrome
Part of Cancer, Genetic & congenital, Hormones & metabolism, Kidney & urinary, Women’s health & pregnancy clinical trials.
This study looks at children with Denys-Drash syndrome who had a kidney transplant to see if they are more likely to develop a type of immune cell overgrowth called lymphoproliferative disorder. It is an observational study, meaning researchers just review medical records without giving any new treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child must be under 18 years old at the time of kidney transplant.
- They must have a confirmed diagnosis of Denys-Drash syndrome (a genetic condition affecting kidney function).
- Doctors must have tested for Epstein-Barr virus (a common virus) at some point—any result is fine.
- The transplant must have taken place between 2000 and 2022 at a participating center in France.
- They must be on immunosuppressant medicines (which lower the body's immune response) after the transplant.
- Your child must not have had a lymphoproliferative disorder (abnormal immune cell growth) or certain other blood cancers before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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