Clin2
NCT07609706Possibly a fitNot yet recruiting

Drug combination for multiple myeloma with moderate liver problems

Multiple Myeloma

Treatments studied

Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy clinical trials.

This study tests a combination of three drugs (belantamab mafodotin, bortezomib, and dexamethasone) for people with multiple myeloma who also have moderate liver problems. The goal is to see if this combination is safe and works well for them.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
20 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older and have a confirmed diagnosis of multiple myeloma.
  • You must have had at least one prior treatment for multiple myeloma, and your disease must have progressed during or after that treatment.
  • You need to have measurable signs of the disease, such as a certain level of M-protein in blood or urine, or increased plasma cells in the bone marrow.
  • You must have either normal liver function or moderate liver impairment, as defined by specific blood tests.
  • If you had a stem cell transplant in the past, it must have been more than 100 days ago, and you must be free of active infections.
  • You must not have certain eye conditions, active bleeding, or serious unstable medical issues.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07614360Not yet recruiting· Phase 2
Belantamab combination for relapsed multiple myeloma

This trial tests a new way of giving a combination of three drugs—belantamab mafodotin, bortezomib, and dexamethasone—for people with multiple myeloma that has come back or stopped responding to earlier treatments. The goal is to see if a different dosing schedule is more effective and safer.

NCT05581875Not yet recruiting· Phase 1/Phase 2
Combination therapy for multiple myeloma after one prior treatment

This trial tests a new combination of drugs for people with multiple myeloma whose cancer did not respond to or returned after one prior treatment with lenalidomide. The goal is to see if this combination is safe and effective.

NCT07227311Recruiting· Phase 2
Belantamab mafodotin combinations for relapsed multiple myeloma

This trial tests a new drug called belantamab mafodotin (a targeted antibody therapy) combined with standard treatments for multiple myeloma that has come back or stopped responding. It looks at three different drug combinations to see which works best for people who have had 1 or 2 prior treatments.

Los Alamitos, California
NCT07334535Not yet recruiting· Phase 4
Combination treatment for newly diagnosed high-risk multiple myeloma

This study tests a combination of four medicines (isatuximab, bortezomib, lenalidomide, dexamethasone) for people with newly diagnosed high-risk multiple myeloma who are not having a stem cell transplant. The goal is to see if this combination can better control the disease and improve outcomes.

Beijing, Beijing Municipality
NCT06679101Recruiting· Phase 3
Belantamab combination vs standard care for newly diagnosed multiple myeloma

This trial tests a new drug combination (belantamab mafodotin plus lenalidomide and dexamethasone) against the usual treatment for people newly diagnosed with multiple myeloma who cannot have a stem cell transplant. It aims to see if the new combination works better.

Mobile, Alabama
NCT07285239Recruiting· Phase 3
Comparing two drug combinations for newly diagnosed multiple myeloma

This trial compares two different combinations of medications for people with newly diagnosed multiple myeloma who are not planning to have a stem cell transplant. It looks at whether adding a targeted antibody drug is as effective as the standard approach.

La Crosse, Wisconsin

Hear when a new Multiple myeloma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.