Clin2
NCT07610486Possibly a fitRecruiting

Better ampicillin dosing for preterm infants

Early Onset SepsisPreterm NeonatesNICUAmpicillinSafety and Pharmacokinetics

Part of Infections clinical trials.

This study gives preterm babies the standard antibiotic ampicillin and checks the amount in their blood to find the best dose. It may help make sure the medicine works well and is safe for babies born early.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
60 people
Ages
birth to 1 week
Study type
Interventional

Who can take part

  • Baby is born at or before 34 weeks and 6 days of pregnancy
  • Baby is less than 7 days old at the start
  • Baby is in the NICU and has been prescribed ampicillin for possible early infection
  • Parent or guardian agrees to the study
  • Baby does not have a confirmed infection or other serious medical conditions

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07460349Recruiting
Extended interval gentamicin dosing in newborns

This study looks at spacing out doses of the antibiotic gentamicin for newborns up to 7 days old who need it. The goal is to make sure the dosing schedule works well and is safe for babies.

London, Ontario
NCT07484633Not yet recruiting· Phase 4
Comparing antibiotic infusion methods for children with sepsis

This study compares two ways of giving antibiotics to children with sepsis: the usual short infusions versus longer or continuous infusions. The goal is to see if one approach works better or is safer.

Budapest
NCT06845332Recruiting
Best treatment choices for newborns with suspected early infection

This trial is testing ways to make the best treatment decisions for newborns who may have an early infection (sepsis). It focuses on babies born at 34 weeks or later and within their first three days of life.

Alkmaar
NCT05977400Not yet recruiting· Phase 3
Long-term health check for premature babies who had antibiotics

This study follows up on babies who took part in the NANO study, which looked at how antibiotics given in the NICU affect health. Researchers will check on these children over time to see how they are doing in the long run.

San Diego, California
NCT06100614Recruiting
Using a blood test to reduce antibiotics in preterm newborns

This study checks if a blood test (presepsin) can help doctors safely stop antibiotics earlier in preterm babies at moderate risk of infection. The goal is to reduce unnecessary antibiotic use.

Amsterdam, North Holland
NCT06377397Not yet recruiting· Phase 3
Antibiotics only when symptoms appear for preterm babies

This trial compares giving antibiotics to all preterm babies at risk of infection versus giving them only if symptoms develop. It aims to find out if waiting is safer and reduces unnecessary antibiotic use.

Chandigarh

Hear when a new Early Onset Sepsis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.