Tranexamic Acid Delivery Methods in Hip or Knee Replacement
Treatments studied
Part of Bones, joints & muscles clinical trials.
This study compares two ways of giving tranexamic acid (a medication that reduces bleeding) during hip or knee replacement surgery. Researchers want to see which method—injected directly into the bone or through the vein—works better and reaches the bloodstream more effectively.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18–80 years
- Scheduled for primary (first-time) total hip or knee replacement for osteoarthritis
- Hemoglobin level of at least 9 g/dL (a measure of red blood cells)
- Good overall health (ASA physical status I–III, meaning no severe organ problems)
- Weight at least 45 kg (about 100 lbs) and BMI under 40 kg/m²
- Able to understand and sign consent forms and attend follow-up visits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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