Testing a new cholesterol medicine against bempedoic acid
Treatments studied
Part of Hormones & metabolism clinical trials.
This study compares two new medicines—obicetrapib and bempedoic acid—to see which one better lowers cholesterol in people whose cholesterol remains high despite taking standard medications. If your cholesterol isn't controlled well enough with current drugs, this trial may help you access an experimental treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have high cholesterol (non-familial) or mixed cholesterol and triglycerides, with heart disease risk
- You have been on a stable maximum-tolerated cholesterol medication (statin, with or without ezetimibe or PCSK9 inhibitor) for at least 8 weeks
- Your LDL cholesterol (bad cholesterol) is between 70–129 mg/dL at screening, despite current treatment
- Your triglycerides are below 500 mg/dL and your kidney function is adequate (eGFR ≥30)
- You have not had a heart attack, stroke, or unstable angina in the past 3 months, and no hospitalization for heart failure in the past 5 years
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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