Blood Pressure and Cholesterol Treatment Study
Treatments studied
Part of Heart & circulation, Hormones & metabolism clinical trials.
This study tests a combination of two new medications (QCZ484 and inclisiran) designed to lower both blood pressure and cholesterol levels. You may be a good fit if you have high blood pressure and high cholesterol that isn't fully controlled by current treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18 to 75 years old
- Diagnosed with high blood pressure (systolic reading between 140–165 mmHg)
- Taking 0, 1, or 2 blood pressure medications at a stable dose for at least 4 weeks
- Diagnosed with high cholesterol not fully controlled by statin medication
- Fasting LDL cholesterol ('bad' cholesterol) between 70–190 mg/dL and triglycerides below 400 mg/dL
- No symptoms of dizziness when standing up from lying down
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests an experimental drug (QLC7401) that may help lower LDL ('bad') cholesterol in people who already have high cholesterol or mixed hyperlipidemia. If you're on stable cholesterol medication but still need more lowering, this trial could offer another option.
This trial tests a new medicine called QLC7401 to lower cholesterol in adults with high cholesterol who are not currently on cholesterol-lowering treatment. It may help reduce the risk of heart problems.
This study tests a new investigational medicine (QLC7401) that aims to lower LDL ('bad') cholesterol when added to your current cholesterol-lowering therapy. If you are already on a statin but your cholesterol is still not low enough, this trial might help you reach your goals.
This trial tests a new medicine that aims to lower LDL (bad) cholesterol in healthy adults. It will help doctors understand how the medicine works in the body and how safe it is.
This study tests two newer cholesterol-lowering medications (inclisiran and alirocumab) together in people who've had heart problems or strokes and cannot tolerate standard cholesterol drugs. The goal is to see if this combination safely lowers cholesterol further and reduces future cardiovascular events.
This study tests an investigational medicine called QLC7401 for people with a genetic condition called heterozygous familial hypercholesterolemia, which causes very high cholesterol. It aims to see if the new medicine can further lower bad cholesterol when added to your usual cholesterol treatments.
Hear when a new Hypercholesterolaemia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.