Study of a cholesterol-lowering combination pill for patients without heart events
Treatments studied
Part of Heart & circulation, Hormones & metabolism clinical trials.
This trial tests a triple therapy pill (bempedoic acid, ezetimibe, and a high-intensity statin) in patients who have extensive plaque in their heart arteries but have never had a heart attack or stroke. It aims to see if this combination can further lower cholesterol and prevent future problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have never taken cholesterol-lowering medication before.
- You have widespread cholesterol plaque in at least 5 sections of your heart arteries, as seen on a special CT scan.
- Your untreated LDL (bad) cholesterol is between 2.6 and 4.5 mmol/L (about 100-174 mg/dL).
- You are not expected to need a procedure to open blocked arteries during the study.
- You have no history of heart attack, stroke, or artery surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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