Understanding Breast Cancer Subtypes in BRCA Carriers
Part of Cancer, Skin clinical trials.
This study examines how different molecular subtypes (patterns of genes and proteins) of breast cancer behave in people with BRCA1 or BRCA2 mutations. By studying tumor samples and medical records, researchers hope to better predict which treatments will work best and predict long-term outcomes for BRCA-positive breast cancer patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have a confirmed BRCA1 or BRCA2 genetic mutation (pathogenic or likely pathogenic)
- You have been diagnosed with HR-positive, HER2-negative breast cancer that has been confirmed under a microscope (histologically confirmed)
- Your medical records from the hospital or clinic visits are available for the research team to review
- A preserved tumor tissue sample from your breast cancer (primary tumor or metastatic site) is available for testing
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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