Lumateperone for Hard-to-Treat Depression in Older Adults
Treatments studied
Part of Mental health clinical trials.
This study tests lumateperone, a new medication added to your current antidepressant, to help treat depression that hasn't improved with other treatments. It's designed for people age 60 and older who have tried at least two antidepressants without success.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 60 or older
- Diagnosed with major depression (non-psychotic, meaning without delusions or hallucinations)
- Depression symptoms are moderate to severe on a standard scale
- Already tried at least two different antidepressants at adequate doses without improvement
- Currently taking an antidepressant at therapeutic dose for at least 6 weeks
- Score of 24 or higher on a brief memory/thinking test (no significant dementia)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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