Botulinum toxin injections for combat-related amputation pain
Treatments studied
Part of Cancer, Pain clinical trials.
This trial tests two ways of injecting botulinum toxin (a medication that relaxes muscles and reduces nerve pain) directly into painful nerve tissue that forms after combat-related amputation. The goal is to find which injection technique works better for chronic neuroma pain—the painful scar tissue that can develop at amputation sites.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a combat-related amputation of a limb
- You have had nerve pain (neuroma pain) for at least 3 months
- Your neuroma pain is confirmed by ultrasound and rates at least 4 out of 10 in severity
- Your pain medications have been stable for at least 2 weeks before joining
- You are able to have an ultrasound-guided injection procedure
- You do not have an active infection, open wound, or bleeding disorder at the injection site
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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