Botox versus numbing shot for post-amputation nerve pain
Treatments studied
Part of Brain & nervous system, Pain clinical trials.
This study compares two treatments—a Botox injection or a numbing medicine injection—for the burning, stabbing pain from a nerve lump (neuroma) that developed after a combat-related amputation. The goal is to see which treatment provides better pain relief for at least 3 months of pain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You had a limb amputation due to a combat injury.
- You have had pain at the amputation site for at least 3 months.
- You have a nerve lump (neuroma) seen on ultrasound that hurts when pressed.
- Your average pain is 4 or more on a 0-10 scale.
- You are on a stable pain medicine plan for at least 2 weeks.
- You have not had Botox injections in the last 6 months or nerve surgery in the last 3 months.
- You do not have an active infection, bleeding disorder, or allergy to the study drugs.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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