Botox vs numbing shot for neuroma pain
Treatments studied
Part of Brain & nervous system, Pain clinical trials.
This study tests a Botox injection compared to a numbing medicine injection to see which better reduces pain from a neuroma (a painful nerve lump) after a limb injury or amputation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You had a limb injury or amputation at least 3 months ago.
- You have pain from a nerve lump (neuroma) that your doctor confirmed with an ultrasound or MRI.
- Your average pain level is at least 4 out of 10 in the past week.
- You have not had Botox treatment in the last 6 months and are not allergic to Botox or numbing medicine.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether platelet-rich plasma (a concentrated blood product believed to promote healing) works better than standard numbing medication when injected into painful nerve tissue (neuroma) that forms after combat-related amputation. The goal is to reduce pain and help you return to daily activities and prosthesis use.
This trial tests a surgical procedure called targeted muscle reinnervation (TMR) to prevent pain after a leg amputation. The goal is to see if rerouting nerves during amputation can reduce phantom limb pain or stump pain.
This trial compares two injection treatments for chronic nerve pain (neuroma pain) that develops after combat-related limb amputation. You would receive either botulinum toxin (Botox) or a local anesthetic injection to see which better relieves your pain.
This trial tests two ways of injecting botulinum toxin (a medication that relaxes muscles and reduces nerve pain) directly into painful nerve tissue that forms after combat-related amputation. The goal is to find which injection technique works better for chronic neuroma pain—the painful scar tissue that can develop at amputation sites.
This Phase 2 trial tests whether injecting incobotulinumtoxin-A near painful nerves can reduce nerve-type pain in the feet for people with diabetes. If you have lasting, fairly symmetrical pain in both feet, the injections may help calm the nerve pain signals.
This study tests whether a specially targeted injection of botulinum toxin (like Botox) around nerves can help reduce pain from CRPS. It aims to see if the treatment is safe and doable for people with long-lasting CRPS.
Hear when a new Pain Management trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.