Combining treatments for long-standing atrial fibrillation

This trial tests two different ablation techniques to treat a type of irregular heartbeat that doesn't go away on its own. It aims to find which approach works better and is safer.

This study compares two types of ablation (a procedure that uses energy to fix irregular heartbeats) for people with persistent atrial fibrillation. It tests whether adding extra treatment to the back of the heart's left upper chamber helps improve outcomes compared to standard treatment alone.

This trial compares two catheter ablation techniques for people with persistent atrial fibrillation (a type of irregular heartbeat that doesn't go away on its own). It will test whether a more extensive ablation (burning more heart tissue) works better than the standard procedure of isolating the pulmonary veins (the veins that bring blood from the lungs to the heart). If you have this condition and have had at least one episode in the past year, this study might help you find a more effective treatment.

This trial tests a new balloon-based catheter procedure to treat persistent atrial fibrillation (a type of irregular heartbeat lasting at least a week). The procedure uses a special energy technique to stop abnormal electrical signals in your heart.

This study tests whether combining a heart procedure (catheter ablation) with a device to close the left atrial appendage (LAAO) is safer or better than blood thinners alone for frail patients 75 years or older with atrial fibrillation and high stroke risk. It aims to find a treatment that reduces stroke while lowering bleeding risks.

This study tests a new way to destroy the tissue causing dangerous heart rhythms using a detailed model of how the heart's electrical signals spread. It may be an option for people with long-lasting atrial fibrillation or hard-to-control ventricular arrhythmias who are already scheduled for a standard ablation procedure.