Clin2
NCT07638982Possibly a fitNot yet recruiting

Axatilimab with CAR-T for high-risk lymphoma

Diffuse Large B Cell Lymphoma (DLBCL)Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell LymphomaHigh-grade B-cell Lymphoma (HGBCL)High-Grade B-Cell Lymphoma, NosPMBCLFollicular Grade 3 Lymphoma

Treatments studied

Part of Blood & lymphatic, Cancer, Digestive system, Immune system & allergy clinical trials.

This trial tests whether adding a drug called axatilimab to the standard CAR-T cell therapy can improve outcomes for people with high-risk large B-cell lymphoma. CAR-T is a treatment that uses your own immune cells to fight the cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
29 people
Ages
8 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have a type of lymphoma called large B-cell lymphoma.
  • You have at least one high-risk feature of the disease.
  • You are eligible for CAR-T therapy as approved by the FDA.
  • Your cancer can be seen on a CT or PET scan.
  • Your organs are working well enough, including heart, lungs, kidneys, and liver.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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