New drug combination for hard-to-treat lymphoma
Part of Cancer clinical trials.
This trial tests a new combination of three drugs (EZH2 inhibitor, glofitamab, and gemcitabine/oxaliplatin) for patients with diffuse large B-cell lymphoma that has stopped responding to or come back after prior treatment. The goal is to see if this combination can shrink the cancer and help patients live longer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18 or older
- Confirmed diagnosis of diffuse large B-cell lymphoma (DLBCL) that has relapsed or become resistant to treatment
- At least one prior treatment that included rituximab (a type of antibody therapy)
- At least one measurable tumor visible on imaging
- Good enough physical condition to tolerate treatment (ECOG score 0–2, meaning able to do light or moderate daily activities)
- Adequate kidney, liver, heart, and blood cell function
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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