Low-dose water pills for kidney disease and high blood pressure
Part of Heart & circulation, Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial tests whether low doses of two different water pills (spironolactone and chlorthalidone)—alone or together—can help Veterans with chronic kidney disease control their blood pressure and protect their kidneys. You would take one of these medications for several months while doctors monitor your kidney function and blood pressure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a U.S. Veteran eligible to receive VA care
- Your kidney function (GFR) is between 15 and 45 mL/min/1.73m² (mild to moderate kidney disease)
- You have high blood pressure, currently controlled with at least one blood pressure medication
- One of your blood pressure medications must be an ACE inhibitor, ARB, or beta-blocker
- Your blood potassium level is normal (between 3.5 and 5.2)
- You have not used certain water pills or potassium-altering drugs in the past 4 weeks
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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