Blood pressure medications for kidney disease in veterans
Part of Heart & circulation, Kidney & urinary, Women’s health & pregnancy clinical trials.
This study compares two blood pressure medications (spironolactone and chlorthalidone), given alone or in combination, to see if they help protect kidneys in people with chronic kidney disease and high blood pressure. The goal is to find a better way to slow kidney decline.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be a US Veteran.
- Your kidney function must be moderately to severely reduced (between 15 and 45 on a kidney test).
- You must have high blood pressure (around 135/85 or higher).
- You must be taking at least one blood pressure medicine, and one of them should be an ACE inhibitor, ARB, or beta-blocker.
- You must not be taking certain 'water pills' or other related medicines within the last 4 weeks.
- You must not have had a heart attack, heart failure hospital stay, or stroke in the past 8 weeks.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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