Blood Pressure Study Using Leucine, Sildenafil, and Metformin
Part of Heart & circulation clinical trials.
This study tests whether a combination of three medications (leucine, sildenafil, and metformin) can help lower blood pressure in people with high blood pressure. Researchers want to see if this three-drug combination works better than existing treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age between 18 and 75 years old
- Systolic blood pressure between 130–160 mm Hg (high but not severely elevated)
- Taking 0, 1, or 2 blood pressure medications (not more than 2)
- Have not taken metformin, sildenafil, or related drugs in the past 8 weeks
- No severe kidney disease or serious heart conditions like recent heart attack or stroke
- No allergies to metformin, sildenafil, or leucine
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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