Study of a new drug for fluid around the lungs in advanced cancer
Treatments studied
Part of Cancer, Lungs & breathing clinical trials.
This trial tests a new drug called JMKX000197 against a standard chemotherapy drug (cisplatin) to see which is better at reducing fluid buildup around the lungs in people with advanced cancer. The goal is to ease breathing and improve quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced cancer that has spread and is confirmed by biopsy or cell sample.
- You have a moderate to large amount of fluid around your lungs that needs to be drained.
- You are able to care for yourself (ECOG score 0-2) and have a life expectancy of at least 3 months.
- Your organs (like liver, kidneys, and bone marrow) are working well enough.
- If you could become pregnant, you must have a negative pregnancy test and agree to use birth control during the study and for 6 months after the last dose.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests an investigational drug called JMKX000197 given into the chest to control fluid buildup caused by cancer. It is for people with advanced solid tumors that have led to a moderate or large pleural effusion requiring drainage.
This trial tests a new drug given directly into the chest cavity to treat fluid buildup caused by non-small cell lung cancer. It may help ease breathing problems and control the fluid.
This study collects fluid that builds up around your lungs (pleural effusion) during a drainage procedure you already need. Researchers test how different drugs affect your cancer cells in the lab to help predict which treatments might work best for you.
This trial tests whether adding a traditional Chinese medicine called Xuan Yin Ning to an existing drug (bevacizumab) can help control fluid buildup around the lung in people with advanced non-small cell lung cancer. The goal is to reduce symptoms like shortness of breath and improve quality of life.
This trial tests a new drug called MT027 for people with advanced cancer that has spread to the lining around the lungs (pleura) and caused fluid buildup. The drug targets a marker on cancer cells called B7-H3. It may help control the fluid and the cancer.
This trial tests a new drug called JMKX005425 for people with advanced solid tumors that have a specific genetic feature called MSI-H or dMMR. If you have this feature and your cancer has not responded to other treatments, this study may offer a new option.
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