Clin2
NCT07670338Possibly a fitNot yet recruiting

Combination treatment for fluid around the lung in advanced lung cancer

Malignant Pleural Effusions (Mpe)

Part of Cancer, Lungs & breathing clinical trials.

This trial tests whether adding a traditional Chinese medicine called Xuan Yin Ning to an existing drug (bevacizumab) can help control fluid buildup around the lung in people with advanced non-small cell lung cancer. The goal is to reduce symptoms like shortness of breath and improve quality of life.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
308 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You have advanced non-squamous non-small cell lung cancer that has not responded to at least one prior treatment.
  • You have a moderate to large amount of fluid on one side of your lung that needs to be drained.
  • You are between 18 and 75 years old.
  • You are able to perform daily activities with some help (ECOG score 0-2).
  • You have a traditional Chinese medicine diagnosis of 'suspension fluid' with fluid in the chest.
  • Your doctor expects you to live at least 3 more months, and you are willing to follow the study schedule.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07649369Not yet recruiting· Phase 2
Study of a new drug for fluid around the lungs in advanced cancer

This trial tests a new drug called JMKX000197 against a standard chemotherapy drug (cisplatin) to see which is better at reducing fluid buildup around the lungs in people with advanced cancer. The goal is to ease breathing and improve quality of life.

Beijing
NCT07332858Recruiting· Phase 1/Phase 2
Study of an experimental drug for lung cancer with fluid in the chest

This trial tests a new drug given directly into the chest cavity to treat fluid buildup caused by non-small cell lung cancer. It may help ease breathing problems and control the fluid.

Beijing, Beijing Municipality
NCT06740019Recruiting· Phase 1
JMKX000197 for malignant pleural effusion in advanced cancer

This trial tests an investigational drug called JMKX000197 given into the chest to control fluid buildup caused by cancer. It is for people with advanced solid tumors that have led to a moderate or large pleural effusion requiring drainage.

Beijing
NCT07636252Recruiting
Testing lung cancer drugs on your fluid sample

This study collects fluid that builds up around your lungs (pleural effusion) during a drainage procedure you already need. Researchers test how different drugs affect your cancer cells in the lab to help predict which treatments might work best for you.

Ramat Gan, Israel
NCT07090525Recruiting· Phase 2
Bevacizumab plus cisplatin vs. cisplatin alone for fluid buildup from cancer

This trial tests whether adding bevacizumab (a drug that blocks blood vessel growth) to cisplatin (a standard chemotherapy) is better than cisplatin alone for controlling fluid buildup caused by adenocarcinoma. If you have not had prior treatment for this fluid, you may qualify.

Qingdao, Shandong
NCT06726564Recruiting· Phase 1
Study of MT027 for malignant pleural effusion

This trial tests a new drug called MT027 for people with advanced cancer that has spread to the lining around the lungs (pleura) and caused fluid buildup. The drug targets a marker on cancer cells called B7-H3. It may help control the fluid and the cancer.

Beijing

Hear when a new Malignant Pleural Effusions (Mpe) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.