Study of genes, gut bacteria, and lifestyle in obesity
Part of Hormones & metabolism clinical trials.
This study looks at how genes, gut bacteria, and lifestyle behaviors relate to weight. Researchers will test a weight-loss medication (tirzepatide) as part of the study to see if it helps people with overweight or obesity.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You are overweight or have obesity, meaning your body mass index (BMI) is more than 27.
- You are willing to provide written consent to participate.
- You do not have type 1 or type 2 diabetes, and you are not pregnant or breastfeeding.
- You do not have serious health conditions like cancer, heart failure, a recent heart attack, stroke, liver cirrhosis, or a mental illness.
- You are not currently taking certain medications (like immunosuppressants, steroids, NSAIDs, or antibiotics within the past 2 weeks) and have no active infections or autoimmune diseases.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how a weight-loss drug called tirzepatide affects your gut bacteria and digestion after you stop taking it. If you are obese and about to start this drug, joining might help you understand how it changes your body.
This study tests a medicine called tirzepatide to see if it helps people with overweight or obesity lose weight, whether or not they also have type 2 diabetes. Tirzepatide is given as an injection and works on hormones that control appetite.
This trial compares two ways to manage weight: taking a GLP-1 medication (like tirzepatide or semaglutide) versus making lifestyle changes without medication. It will help researchers learn which approach works best for people with overweight or obesity.
This Phase 2 study tests whether tirzepatide can improve how your body handles fat (especially in people with overweight or obesity) and reduce fat-related “lipotoxicity.” It may help with body fat function and related health markers, but you must meet specific health and medication rules.
This study tests whether combining a weight-loss medication called tirzepatide (also known as Mounjaro) with a supervised exercise program helps people lose weight and improve their overall health. You'll be in the study for about four months, and you'll get support and monitoring.
This trial tests if the weight loss medication tirzepatide can help young adults (18–40) with obesity and high blood pressure lower their blood pressure. It compares standard care to weight loss with tirzepatide.
Hear when a new Obesity & Overweight trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.