Tirzepatide for fat-related body dysfunction in overweight adults
Treatments studied
Part of Hormones & metabolism clinical trials.
This Phase 2 study tests whether tirzepatide can improve how your body handles fat (especially in people with overweight or obesity) and reduce fat-related “lipotoxicity.” It may help with body fat function and related health markers, but you must meet specific health and medication rules.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You don’t have diabetes: your fasting glucose must be under 126 mg/dL while not taking any glucose-lowering medications
- You are 18 to 70 years old and have a BMI between 27 and 39.9
- If your BMI is 27–29.9, you need at least one weight-related issue (like high blood pressure, abnormal cholesterol/triglycerides, or prediabetes-related conditions)
- You have not had bariatric (weight loss) surgery or liposuction
- Your weight has not changed by more than 2 kg in the last 6 weeks
- You are not pregnant or breastfeeding, and you are not using weight-loss or glucose-raising medicines (including GLP-1 medicines) currently or within the last 3 months
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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