Study of mazdutide for heart artery plaque in people who are overweight
Treatments studied
Part of Heart & circulation, Hormones & metabolism clinical trials.
This study tests whether mazdutide, a medicine that may help with weight and blood sugar, can reduce plaque buildup in the heart's arteries. It is for people who are overweight or obese and have some narrowing in their heart arteries but do not need immediate procedures like stents.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are overweight or obese (BMI 24 or higher, with certain conditions like high blood pressure, diabetes, or fatty liver).
- You have heart artery narrowing between 30% and 70%, confirmed by a recent heart scan or angiogram.
- You have not had severe heart disease, stroke, or pancreatitis recently.
- You are not currently taking weight-loss or diabetes medicines like GLP-1 drugs.
- You are willing to attend follow-up visits and follow the study plan.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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