Lymph node surgery for moderate Alzheimer's disease
Part of Brain & nervous system, Mental health clinical trials.
This trial tests a surgery that connects lymph vessels in the neck to help clear waste from the brain, which may slow down memory loss in people with moderate Alzheimer's disease. It is for patients who have not improved with standard medications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 50 and 80 years old.
- You have been diagnosed with moderate Alzheimer's disease and have had memory or thinking problems for at least 6 months.
- Your memory test score is between 10 and 20 points.
- You have been on the same Alzheimer's medication for over 6 months without clear improvement.
- You have a caregiver who can come with you to visits and help with evaluations.
- You are healthy enough to have surgery and anesthesia, and you do not have other brain conditions like stroke or brain tumor.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a surgical treatment for Alzheimer's disease that aims to improve drainage of fluid from the brain. It is for people aged 30 to 80 with moderate to severe symptoms and who can tolerate surgery.
This study is for people with Alzheimer's disease who have already had a neck surgery to improve fluid drainage (called DC-LVA). Researchers want to see how this surgery affects thinking and memory over time, and they will follow participants to learn more.
This trial tests a surgical procedure that connects lymphatic vessels in the neck to help clear waste from the brain in people with moderate-to-severe Alzheimer's disease. The goal is to see if this can improve thinking and memory.
This study tests a new surgical treatment for Alzheimer's disease. The surgery aims to improve drainage in the neck to help clear waste from the brain. This is a first-of-its-kind pilot study to see if it is safe and might help thinking and memory.
This trial tests a neck surgery (lymphaticovenous and lymph node-to-vein anastomosis) to see if it improves symptoms in people with Alzheimer's disease linked to a brain lymphatic circulation disorder. It focuses on those with moderate-stage Alzheimer's and confirmed amyloid buildup.
This study tests a surgery to reconnect tiny lymph vessels in the neck to help drain waste from the brain, which may slow or improve severe Alzheimer's symptoms. It is for people with advanced Alzheimer's who have not gotten better with standard treatments.
Hear when a new Alzheimer’s disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.