A new clip to repair leaky mitral valve without open-heart surgery
Part of Heart & circulation clinical trials.
This study tests a new clip system to repair a leaky mitral valve without open-heart surgery, using a thin tube from a vein in your leg. It's for people who have severe mitral regurgitation and are at high risk for traditional surgery, to see if it can reduce symptoms and improve heart function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 18 years old.
- You must have significant mitral regurgitation (a leaky mitral valve) confirmed by heart imaging, with symptoms or reduced heart function.
- You must be considered high risk for open-heart surgery by your care team.
- You must be able to have the procedure done through a vein in your leg (transcatheter approach), and your valve anatomy must be suitable for a clip.
- You cannot have certain other heart conditions, recent bleeding, infections, or history of prior mitral valve surgery or clip.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests Valveclip, a catheter-based way to repair a mitral valve that is leaking badly. It may help people who are high-risk for open surgery by aiming to reduce the leak with a less invasive approach.
This study tests a new clip procedure (CardioClip) to repair a leaky mitral valve in people with heart failure. It aims to see if the clip can improve symptoms and heart function.
This trial studies whether a device called GeminiOne can safely and effectively repair a leaky mitral valve using a catheter-based “clip” technique. It may help patients who have moderate-to-severe or severe valve leakage but are considered too high-risk for open surgery.
This trial tests a new device, called MRace, that is placed with a thin tube into the heart to fix a leaky mitral valve. It's for people whose valve is too complex for the usual clip repair, and who are too high-risk for open-heart surgery.
This trial tests a clip-based procedure (TEER) to fix a severe leak in the mitral valve for people who have symptoms or heart changes but are at low to medium risk for surgery. The goal is to see if this less invasive option works well and is safe.
This study is testing a new assist system to help doctors perform a minimally invasive procedure (MitraClip) that clips the leaky mitral valve without open-heart surgery. It is for people with severe mitral regurgitation who cannot safely have surgery or choose not to.
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