CoQ10 and vitamin E for radiation side effects
Part of Cancer, Digestive system, Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial tests whether taking CoQ10 and vitamin E supplements can reduce the side effects of radiation therapy for certain cancers. If you are receiving radiation for prostate, uterine, or anal cancer, this study might help you manage treatment-related symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have prostate, uterine (endometrial or cervical), or anal cancer that was confirmed by biopsy.
- You are scheduled to receive at least 15 sessions of radiation therapy (with or without chemotherapy) as part of your treatment.
- You are 19 years or older.
- You are generally able to care for yourself (performance status 0-2).
- You can swallow soft-gel capsules.
- You do not have conditions that affect how your body absorbs food or medicine, like severe bowel disease or prior stomach/bowel surgery.
- You agree to limit alcohol to 2 drinks or less within 6 hours before and after taking the supplements.
- You agree to stop taking any vitamins or supplements containing vitamin E or CoQ10 while on the study.
- You agree to use effective birth control if you or your partner can become pregnant.
- You have adequate blood counts and liver/kidney function as shown by recent lab tests.
- You are not taking blood thinners or antiplatelet drugs that cannot be paused for at least 2 weeks before starting the study.
- You do not have bleeding disorders, retinitis pigmentosa, severe fibrosis, or a history of stroke or bleeding in the brain.
- You do not have uncontrolled high blood pressure (systolic ≥140 or diastolic ≥90).
- You are not allergic to vitamin E, CoQ10, or ingredients like soy or gelatin.
- You are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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