How NOTCH2NLC gene changes affect NIID in one family
This trial studies a family with a gene change (NOTCH2NLC) that can cause NIID, a disease that affects nerves and the brain. It aims to understand how different gene variations relate to symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are part of a single family that carries changes in the NOTCH2NLC gene linked to a condition called NIID (which affects nerves and brain).
- You are between 18 and 85 years old.
- You are willing to have a genetic test (including special DNA reading) and a small skin sample taken.
- You can agree to take part by signing a consent form.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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