Infliximab Eye Drops for Sjögren's Dry Eye
Part of Bones, joints & muscles, Eyes & vision, Immune system & allergy, Mouth & dental, Skin clinical trials.
This trial tests whether an eye drop version of infliximab, a medication that reduces inflammation, can help people with Sjögren's syndrome who have severe dry eye. You would keep taking your current medications and add these drops to see if they improve symptoms and eye surface damage.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have Sjögren's syndrome (diagnosed by a rheumatologist).
- You have been on a stable dose of a non-biologic medication for your immune system for at least 12 weeks.
- You have severe dry eye: your eye staining score is 6 or higher and your dry eye symptom score is 33 or higher.
- You have not used steroid or other immune-suppressing eye drops in the past 30 days.
- You are not pregnant, breastfeeding, or planning to become pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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