Clin2
NCT07675824Possibly a fitNot yet recruiting

New treatment for open-angle glaucoma or high eye pressure

Primary Open Angle Glaucoma (POAG)Ocular Hypertension (OHT)

Part of Eyes & vision clinical trials.

This trial tests an investigational drug called REGN22530 for people with mild to moderate primary open-angle glaucoma or ocular hypertension (high eye pressure). The goal is to see if it can safely lower eye pressure and protect vision.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
271 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have primary open-angle glaucoma or high eye pressure that is mild to moderate.
  • Your vision in the study eye is at least 20/200 (with glasses or contacts).
  • Your vision in the other eye is at least 20/80 (with glasses or contacts).
  • You have not had certain types of glaucoma surgery in the past (like trabeculectomy or a tube shunt).
  • You have not had a laser treatment for glaucoma in the last 6 months (like SLT) or certain other laser in the last year.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06921317Recruiting· Phase 1/Phase 2
Gene therapy for advanced glaucoma

This trial tests a gene therapy treatment called GVB-2001 for people with primary open angle glaucoma. It involves a one-time injection into the eye to help lower eye pressure, and could be an option if you have tried other treatments that haven't worked well enough.

Suzhou, Jiangsu
NCT07335211Recruiting· Phase 3
Testing a new eye drop for glaucoma or high eye pressure

This trial tests a new medicine called HUC3-637 for people with primary open-angle glaucoma or ocular hypertension. It aims to see if it safely lowers eye pressure.

Seoul
NCT07661329Recruiting· Phase 3
Comparing a new eye drop to a standard one for glaucoma and high eye pressure

This study tests a new eye drop against an existing one to see which better lowers eye pressure in people with open-angle glaucoma or ocular hypertension. You may be able to join if you have high eye pressure in both eyes that needs treatment and you are at least 18 years old.

Beverly Hills, California
NCT07662759Recruiting· Phase 3
Study of TFC-003 for open-angle glaucoma or high eye pressure

This trial tests a new eye drop combination (TFC-003) to lower eye pressure in people with primary open-angle glaucoma or ocular hypertension. It compares the new drug to existing treatments to see if it works better or is safer.

Seongnam
NCT06865235Recruiting
Glaucoma and cataract surgery with a new device

This trial tests a surgery that combines cataract removal with a new technique to lower eye pressure in people who have both primary open-angle glaucoma and cataracts. It aims to see if this combined surgery is safe and effective.

Belo Horizonte, Minas Gerais
NCT07770685Not yet recruiting· Phase 1/Phase 2
Study of a new eye drop for advanced glaucoma

This trial tests an investigational eye drop called ASP2767 to see if it is safe and can help slow or prevent further vision loss in people with advanced glaucoma-related optic nerve damage.

Hear when a new Ocular Hypertension (OHT) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.