Statins and folic acid for unstable carotid plaque
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests if adding folic acid to a statin can help stabilize plaques in the carotid artery (neck artery) to prevent stroke. You may qualify if you have carotid plaque and are not already on certain supplements.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a carotid (neck artery) plaque confirmed by ultrasound or CT scan.
- You are between 18 and 75 years old.
- You can attend all 6 months of study visits and tests.
- You have not had prior surgery or stenting for carotid plaque.
- You do not have severe liver or kidney disease, cancer, or an autoimmune condition.
- You are not pregnant, breastfeeding, or taking certain vitamins (B6, B12, multivitamins).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests a medication called alirocumab (given as an injection) to see if it can stabilize the fatty buildup (plaque) in the carotid artery that caused your recent stroke or mini-stroke. It might help reduce the risk of another event.
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This trial looks at specific markers in the blood to better understand unstable plaque in the carotid artery. It may help doctors identify which patients are at higher risk for stroke.
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