Medication under the tongue during transfer for acute stroke treatment
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests a medication called edaravone dexborneol that is given under the tongue while you are being transferred to a hospital for a procedure to remove a blood clot from your brain. It is hoped that this medication can help protect your brain during the journey and improve recovery after the stroke.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You had an acute ischemic stroke (a stroke from a blocked artery in the brain) and it has been less than 6 hours since you were last known to be well.
- Your stroke is considered severe or involves a large blood vessel, and you are being transferred to a hospital that can do a procedure to remove the clot (thrombectomy).
- You are able to take medication placed under your tongue and are not deeply unconscious.
- You do not have severe liver or kidney problems, and you are not pregnant or breastfeeding.
- You have not had a major disability before this stroke (you were mostly independent).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial tests a medicine called edaravone dexborneol to see if it helps people recover from a recent ischemic stroke (a stroke caused by a blocked blood vessel). The medicine is given within 48 hours of the stroke, and the study will compare how well it works and if it is safe.
This trial tests whether giving a clot-busting drug (tenecteplase) before transferring you to a hospital that can do a procedure to remove the clot improves outcomes for people who had a stroke up to 24 hours earlier. You may qualify if you have a blockage in a large artery in the front of your brain and can still get the procedure.
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