Stroke clot-busting drug before transfer for artery clearing
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether giving a clot-busting drug (tenecteplase) before transferring you to a hospital that can do a procedure to remove the clot improves outcomes for people who had a stroke up to 24 hours earlier. You may qualify if you have a blockage in a large artery in the front of your brain and can still get the procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- Your stroke symptoms started between 4.5 and 24 hours before treatment.
- You had a stroke caused by a blockage in a large artery in the front part of your brain.
- You were able to do daily activities without help before the stroke.
- A brain scan shows a certain pattern that indicates you might benefit from this treatment.
- You are planned to be transferred for a procedure to remove the clot.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial compares two clot-dissolving medications (tenecteplase and reteplase) given before a procedure to remove a large clot from a brain artery. It aims to see which drug works better for people who have had an acute ischemic stroke and are eligible for both treatments.
This trial tests if a clot-busting drug called Tenecteplase helps people with a severe type of stroke in the back of the brain (basilar artery occlusion) when given 4.5 to 24 hours after symptoms start. Patients will then be moved to a hospital that can remove the clot. The goal is to see if the drug improves recovery.
This trial tests if giving a clot-busting drug (tenecteplase) directly into the brain artery after a successful clot-removal procedure can improve outcomes for people with a major stroke. It is for patients who had a large vessel blockage and received endovascular thrombectomy within 24 hours of symptoms starting.
This trial tests a new clot-busting medicine called tenecteplase, given directly into the blood vessel in the brain, to treat strokes caused by a blockage in a medium-sized artery. The goal is to see if it can help restore blood flow and reduce disability, especially for patients who can be treated within 24 hours of stroke onset.
This trial tests whether giving a clot-busting drug (alteplase) directly into the brain artery after a successful clot removal improves recovery in people with severe stroke. It is for patients who have had a thrombectomy and still have a large blocked artery in the front of the brain.
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